The polypeptides, and the polynucleotides encoding for them, described herein are IL-21 antagonists that bind with specificity and exhibit an EC50 that is not detectable in receptor binding studies. These molecules have mutations in the D helix of the IL-21 molecule, and can be used to inhibit the activity of IL-21 with its cognate receptor.


< Attachment of second harmonic-active moiety to molecules for detection of molecules at interfaces

< Optical heterodyne surface plasma wave detecting method and apparatus

> Enzymatic synthesis of polymers

> Biosensor and measuring apparatus for biosensor

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