The present invention provides isolated laminin 10, methods for making recombinant
laminin 10, host cells that express recombinant laminin 10, and methods for using
the recombinant laminin 10 to accelerate the healing of injuries to vascular tissue,
and to promote cell attachment and migration. The present invention also provides
nucleic acid sequences encoding full length human laminin 5 chain, expression
vectors and host cells thereof, and isolated full length human laminin 5
polypeptide chain.