An all-optical switch includes a microsphere optical resonator coated with a conjugated polymer. A signal light beam propagating along a first SPARROW waveguide defining a throughput channel is evanescently coupled into the resonant whispering gallery modes (WGM) of the microsphere, and out of the microsphere onto a second SPARROW waveguide defining a drop channel. A secondary switching light beam is used to heat the microsphere resonator, thereby shifting its resonant frequency so that it no longer overlaps with the signal beam frequency. Light coupling into the microsphere and onto the drop channel is thus eliminated, and the signal beam is switched from the drop channel to the throughput channel. The time constant for the WGM resonant frequency shifting was about 165 ms, indicating thermo-optic switching capabilities at speeds on the order of 100 microseconds for high-Q modes. Multiple frequencies or channels can be routed using a switch configuration with multiple microspheres and drop channels.