Compounds of formula (I)
##STR1##
are novel VR1 antagonists that are useful in treating pain, inflammatory thermal
hyperalgesia, urinary incontinence and bladder overactivity, wherein X1,
X2, X3, X4, X5, R5, R6,
R7, R8a, R8b, R9, Z1, Z2
and L are as defined in the description.
