The invention provides a method of transferring in vivo a molecule into a striated
muscle cell. More specifically, a method of the invention comprises contacting
in vivo a striated muscle cell with a molecule, and electrically stimulating the
muscle cell with one or more unipolar pulses of an electric field intensity ranging
from 1 to 800 V/cm2. In one embodiment, the molecule is a nucleic acid
encoding a protein of interest. For example, the invention provides methods of
promoting angiogenesis and hemostasis.
