An dermatological agent for external use is disclosed which contains a chromanol
glycoside represented by the following general formula (1)
##STR1##
(wherein R1, R2, R3, and R4 which
may be the same or different, each represent a hydrogen atom or a lower alkyl group,
R5 represents a hydrogen atom, a lower alkyl group, or a lower acyl
group, X represents a monosaccharic residue or an oligosaccharic residue optionally
having the hydrogen atom of the hydroxyl group in the saccharic residue substituted
with a lower alkyl group or a lower acyl group, n represents an integer in the
range of 0-6, and m represents an integer in the range of 1-6). This is a novel
dermatological agent for external use which excels in stability and percutaneous
absorbency, manifests an effective action safely at a small application rate, and
effectively prevents and cures the dermopathy. It is very useful as an agent for
preventing and curing the disorders caused by the ultraviolet light, an agent for
preventing and allaying the sedimentation of pigment in the skin, an agent for
beautifying the skin in white, an agent for preventing the senescence of the skin,
an agent for activating cells, an agent for preventing and curing the dermopathy,
and a cosmetic preparation.