The present invention relates to novel compounds of the Formula (I): 1
which act as MCH receptor antagonists. These compositions are useful in
pharmaceutical compositions whose use includes prophylaxis or treatment
of improving memory function, sleeping and arousal, anxiety, depression,
mood disorders, seizure, obesity, diabetes, appetite and eating
disorders, cardiovascular disease, hypertension, dyslipidemia, myocardial
infarction, binge eating disorders including bulimia, anorexia, mental
disorders including manic depression, schizophrenia, delirium, dementia,
stress, cognitive disorders, attention deficit disorder, substance abuse
disorders and dyskinesias including Parkinson's disease, epilepsy, and
addiction.