A prefilled syringe of cartridge barrel having a tamper evident closure. Tamper evidence is provided by: a frangible tip seal which is integral with the tapered tip of the barrel; a frangible tip cap covering the tip, the tip seal and a portion of the distal end of the barrel; and an overwrap covering the frangible tip cap and the distal end of the barrel sealed to the distal end of the barrel by a tamper evident seal. The tapered tip is optionally equipped with a luer collar to receive an external luer connector. Alternatively, the tapered tip can be provided with a bore therethrough which can be closed with an elastomeric plug and the external connector can be a tubing conduit.

 
Web www.patentalert.com

< Method for improving the stability of linear DNA in cell-free in vitro transcription/translation systems

< Methods and compositions for diagnosing and monitoring transplant rejection

> Rapid, immunochemical process for measuring thiopurine methyltransferase

> Oligonucleotides and methods for detecting hepatitis C viral nucleic acids

~ 00209