The present invention relates to an antigenic fusionprotein, which carries multiple
Gal1,3Gal epitopes. The fusion protein according to the invention may also
be comprised of a heavily glycosylated mucin part, which mediates binding to selectins,
such as PSGL-1, and a part, which exhibits immunoglobulin properties, such as the
Fc part of IgG. The fusionprotein according to the invention is preferably used
as an absorber to prevent a hyperacute rejection of a xenotransplant, such as a
pig tissue or organ transplanted into a human patient. In addition, the invention
relates to a method for the prevention of hyperacute rejection reaction in a patient
who is to receive a xenotransplant.