A medical sequential syringe apparatus has two or more fluids of predetermined volume dispensed therefrom. The apparatus includes a tubular cartridge containing fluid is sealed at one end by a membrane with a hollow tubular spike mounted at one end of the body facing inwardly into the tubular body. A plunger mounted within the tubular body moves the cartridge toward the spike to puncture the membrane and allow the fluid to flow from the cartridge through the hollow of the spike out of the tubular body.