A flexible clip applier includes a flat wire wound tubular coil, a pair of jaws
at the end of the coil, end effector wires extending through the coil and coupled
to the jaws, and a clip-advancing wire extending through the coil. A proximal handle
is adapted to impart tensile force the end effector wires and the tubular coil,
and compressive force to the clip-advancing wire and tubular coil to thereby effect
advancement of a clip into the jaws and over tissue compressed between the jaws,
and deformation of the clip over the tissue.