For preventing the blooming phenomenon, there is provided an image pickup apparatus comprising a solid-state image pickup device adapted for a first readout method in which plural pixels are added to be read and a second readout method in which plural pixels are not added; and a circuit for applying a predetermined substrate voltage common to the first and second readout methods in an exposure period of the solid-state image pickup device and applying a predetermined substrate voltage corresponding to each readout method of the solid-state image pickup device in a period from the end of exposure of the solid-state image pickup device to the start of transfer to the signal transfer channel.