A porous -tricalcium phosphate material for bone implantation is provided.
The multiple pores in the porous TCP body are separate discrete voids and are not
interconnected. The pore size diameter is in the range of 20-500 m, preferably
50-125 m. The porous -TCP material provides a carrier matrix for
bioactive agents and can form a moldable putty composition upon the addition of
a binder. Preferably, the bioactive agent is encapsulated in a biodegradable agent.
The invention provides a kit and an implant device comprising the porous -TCP,
and a bioactive agent and a binder. The invention also provides an implantable
prosthetic device comprising a prosthetic implant having a surface region, a porous
-TCP material disposed on the surface region and optionally comprising at
least a bioactive agent or a binder. Methods of producing the porous -TCP
material and inducing bone formation are also provided.