The invention relates to a method of computing the transformation which transforms two different images (10, 10) of an object one into the other while describing the motion or deformation of the object. In accordance with the method first the local transformation parameters are computed for sub-regions (1, 2, 3, 4, 5). By choosing the sub-regions so as to be sufficiently small, a rigid transformation can be used for this purpose. Starting from at least one first predetermined sub-region (1), the local transformation parameters of the neighboring sub-regions (2, 3, 4, 5) are successively computed, the starting values on which each computation is based being the already determined local transformation parameters of neighboring sub-regions. Using the local transformation parameters thus determined for sub-regions, the overall transformation can subsequently be computed.

 
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