An endoscope assembly is disclosed having a housing adapted to be manipulated by medical personnel, such as a surgeon. An elongated lens tube has one end secured to the housing while an elongated stage is removably secured to the housing so that the stage encompasses and is coaxial with the tube. The stage together with the lens tube are adapted for insertion into the cavity of a body. A lens assembly provided within the lens tube relays the optical image from the free end of the stage to the housing. A lens assembly within the housing, furthermore, varies the magnification of the image between macroscopic magnification and microscopic magnification in which tissue may be examined on a cellular level. For macroscopic magnification, white light is transmitted through the lens tube as well as reflected back from the target tissue through the lens tube and to the housing. For microscopic examination, laser radiation is utilized in lieu of the white light illumination. A line scanning confocal assembly contained within the housing enables microscopic examination of the target tissue at varying levels into the tissue from the end of the stage.