The present invention provides a novel compound having an excellent corticotrophin-releasing-factor
receptor antagonistic activity. That is, it provides a compound represented by
the following formula, a pharmacologically acceptable salt thereof or hydrates
thereof.
##STR1##
Wherein A, B and D are the same as or different from each other and each
represents a group represented by the formula —(CR1R2)m—
(wherein R1 and R2 are the same as or different from each
other and each represents a C1-6 alkyl group etc.), —NR3—
(wherein R3 represetns hydrogen etc.) etc.; E and G are the same as
or different from each other and each represents a group represented by the formula
—(CR6R7)p— (wherein R6and
R7 are the same as or different from each other and each represents
hydrogen etc.; and p represents an integer of 0, 1 or 2); J represents a carbon
atom or nitrogen atom, each substituted with C1-6 alkyl group optionally
substituted with a halogen atom, etc.; K and L are the same as or different from
each other and each represents carbon atom or nitrogen atom; M means hydrogen,
a halogen atom, an optionally substituted C1-6 alkyl group etc.; and
the partial structure means a single or double bond.