The present invention provides a recombinant adenovirus comprising coat proteins that lack native binding. In particular, the present invention provides a recombinant adenovirus comprising a penton base protein and a fiber protein, wherein the penton base protein and the fiber protein lack native binding. The present invention further provides a recombinant adenovirus comprising (a) a penton base protein that lacks native binding and (b) a nonnative amino acid sequence that binds a cell-surface binding site.

 
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< DNA transfection system for the generation of infectious influenza virus

> Functionalized heterocycles as modulators of chemokine receptor function and methods of use therefor

> Azabicyclic-phenyl-fused-heterocyclic compounds for treatment of disease
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