A novel tyrosine-inducible tyrosine ammonia lyase enzyme was isolated from the
yeast Trichosporon cutaneum. This enzyme has a higher activity for tyrosine
than for phenylalanine and is useful for the production of para-hydroxycinnamic
acid directly from tyrosine. The gene encoding this enzyme was sequenced using
3 and 5 RACE cloning of the TAL cDNA and the gene was expressed
in the yeast Saccharomyces cerevisiae and in the bacterium Escherichia
coli.