Novel ligand antagonists of the RAR receptors have the following structural formula (1): 1 in which A is a CH.sub.2, CHOH, C.dbd.O or C.dbd.N--OH radical or a sulfur or selenium atom; B is a radical selected from among those of formulae (a) to (f): 2 and Ar is a radical selected from among those of formulae (g) to (i): 3