Interactive patient education system for use in operatory or office settings, provides interactive 3-D animations, graphics and other media, enabling real-time markup and customization to better illustrate and communicate not only generic information, but the individual patient's physiology, treatment options, and anticipated outcomes. Preferred embodiments are portable, computer-implemented, interactive multimedia educational tools. Import of patient-specific graphics, video and audio contributes to full-custom educational content to optimize patient understanding.