An inverse dispersion fiber having a large effective area and a transmission system that incorporates the fiber for providing dispersion and dispersion slope compensation in a transmission fiber. The large-effective-area inverse dispersion optical fiber (IDF) has a negative dispersion and a negative dispersion slope. The effective area, A_eff, of the IDF preferably is greater than approximately 31 micrometers squared (m²) at a transmission wavelength of approximately 1550 nm. The large-effective-area IDF is suitable for use with super-large-effective-area (SLA) transmission fiber for compensating dispersion in the SLA transmission fiber while reducing nonlinear effects between wavelength channels and cabling loss, which is especially advantageous in transoceanic and long-haul terrestrial systems. These nonlinear effects are inversely related to the effective area of the fiber (i.e., nonlinearities1/A_eff). Thus, an increase in the effective area of the fiber translates into a decrease in nonlinear interactions, which increases bandwidth capabilities and limits signal degradation. Furthermore, the large-effective-area IDF of the present invention has very desirable transmission properties. The present invention also provides a transmission system comprising at least one of the large-effective-area IDF optical fibers of the present invention. Furthermore, A_eff can be made large without having to increase the ratio, R_a, of the diameter of the core to the diameter of the trench region.