An inbred cantaloupe line, designated 442, is disclosed. The invention relates to the seeds of inbred cantaloupe line 442, to the plants of inbred cantaloupe line 442 and to methods for producing a cantaloupe plant, either inbred or hybrid, by crossing the inbred line 442 with itself or another cantaloupe line. The invention further relates to methods for producing a cantaloupe plant containing in its genetic material one or more transgenes and to the transgenic plants produced by that method and to methods for producing other inbred cantaloupe lines derived from the inbred 442.