An improvement in a method of treating benign gynecological disorders is described.
In the method, treatment of a benign gynecological disorder with a composition
comprised of a gonadotropin releasing hormone (GnRH) compound and an estrogenic
compound, and optionally, an androgenic compound, is extended to premenopausal
women who are not receiving an exogenously supplied progestin on a regular or periodic
basis. Treatment in accord with the invention does not increase significantly the
risk of endometrial hyperplasia. The method is also suitable for contraception.