A compound of formula (I), 1
wherein, n is 0 or 1; R6 and R7 are hydrogen, or together form a carbonyl
oxygen; R1 is selected from the group consisting of hydrogen; --N(Z)Y and
--C(Z)Y wherein; when R1 is --N(Z)Y, then: Y is selected from hydrogen,
or the following, where G denotes the point of connection to the nitrogen
atom in N(Y)Z (i-v); Z is selected from hydrogen or X1; Q is selected
from hydrogen or W; the groups W are independently selected from the
group consisting of alkyl, alkenyl, alkynyl, heteroalkyl, aryl,
heteroaryl, arylalkyl and heteroarylalkyl of 1 to 20 atoms, the groups X1
are independently selected from the group consisting of alkyl, alkenyl,
alkynyl, heteroalkyl, acyl, arylacyl, heteroarylacyl, aryl, heteroaryl,
arylalkyl and heteroarylalkyl of 1 to 20 atoms, when R1 is --C(Z)Y, then:
Y is selected from the group consisting of two hydrogen atoms, a double
bonded oxygen to form a carbonyl, and a triple bonded nitrogen to form a
nitrile, Z is absent, or is selected from hydrogen or U, wherein U is
selected from the group consisting of alkyl, alkenyl, alkynyl,
heteroalkyl, aminoalkyl, aminoaryl, aryloxy, alkoxy, heteroaryloxy,
aminoaryl, aminoheteroaryl, thioalkyl, thioaryl or thioheteroaryl, acyl,
arylacyl, heteroarylacyl, aryl, heteroaryl, arylalkyl and heteroarylalkyl
of 1 to 20 atoms, when R1 is H, at least two of the groups R2, R3, R4 and
R5 are selected from the group consisting of --OX2 or --N(T)Y, and the
others are independently selected from hydrogen, --OH, --OX2, --N(T)Y,
wherein Y is as defined above, T is selected from hydrogen or X2; and X2
is independently selected from alkyl, alkenyl, alkynyl, heteroalkyl,
aryl, heteroaryl, arylalkyl or heteroarylalkyl of 1 to 20 atoms, When R1
is N(Z)Y or C(Z)Y, at least one of the groups R2, R3, R4 and R5 are
selected from the group consisting of --OX2 or --N(T)Y, and the others
are independently selected from hydrogen, --OH, --OX2, --N(T)Y, wherein Y
is as defined above, T is selected from hydrogen or X2; and X2 is
independently selected from alkyl, alkenyl, alkynyl, heteroalkyl, aryl,
heteroaryl, arylalkyl or heteroarylalkyl of 1 to 20 atoms.
