Disclosed is a method of producing teicoplanin. The method includes
purifying teicoplanin from a culture broth, obtained by culturing
microorganisms capable of producing teicoplanin by a porous adsorption
resin under selective elution conditions and recovering highly pure
teicoplanin using activated carbon and/or ultrafiltration. In this
regard, the method can further include ultrafiltration as pre-treatment
before the culture broth is adsorbed into the porous adsorption resin so
as to increase the purity of teicoplanin.