This invention is directed to compounds which are selective antagonists
for melanin concentrating hormone-1 (MCH1) receptors. The invention
provides a pharmaceutical composition comprising a therapeutically
effective amount of the compound of the invention and a pharmaceutically
acceptable carrier. This invention provides a pharmaceutical composition
made by combining a therapeutically effective amount of the compound of
this invention and a pharmaceutically acceptable carrier. This invention
further provides a process for making a pharmaceutical composition
comprising combining a therapeutically effective amount of the compounds
of the invention and a pharmaceutically acceptable carrier. This
invention also provides a method of reducing the body mass of a subject
which comprises administering to the subject an amount of a compound of
the invention effective to reduce the body mass of the subject. This
invention further provides a method of treating a subject suffering from
depression and/or anxiety which comprises administering to the subject an
amount of a compound of the invention effective to treat the subject=s
depression and/or anxiety. This invention further provides a method of
treating a subject suffering from a urinary disorder.