The invention provides a noxious organism-controlling agent effective to control pests that have acquired a resistance to conventional Bt agents, and which has activity on Coleoptera pests. Also, the invention provides a microbe, Bacillus thuringiensis serovar galleriae SDS502 strain, that produces a toxic protein. This toxic protein can serve as the active ingredient in a noxious organism-controlling composition. The invention provides a protein having pesticidal activity that is produced by the Bacillus thuringiensis serovar galleriae SDS502 strain, and a protein having an addition, deletion or substitution of a plurality of amino acids and having similar pesticidal activity. The invention also provides a DNA encoding protein having pesticidal activity, a microbe transformed with the DNA, and a plant transformed with the DNA and its seed.