CETP Inhibitors have improved solubility and bioavailability in a lipophilic vehicle comprising a digestible oil, a lipophilic solvent, or a surfactant. Preferred such compositions are self-emulsifying or self-microemulsifying, and comprise

• 1. a CETP inhibitor;
• 2. a cosolvent;
• 3. a surfactant having an HLB of 1 to 8;
• 4. a surfactant having an HLB of over 8 to 20; and
• 5. optionally, a digestible oil.