A method and system for managing agricultural product information, and for facilitating the controlled sale, distribution, and use of agricultural products provides a single data entry process for submitting agricultural product registration applications and renewals for a plurality of jurisdictions (states). A single username and password can be used to access a plurality of state databases. State data can be easily cross-referenced and indexed against federal product registration data. Also provided is a system and process of field inspection and enforcement of registration requirements for agricultural products, wherein universal product codes (UPCs) may be scanned into a portable data terminal and be used to check the approval status of a product found in a retailer's store.