The invention concerns a method for producing a controlled-release pharmaceutical
preparation with a particle-containing coating, the coating being derived from
an aqueous dispersion of a film-forming water insoluble polymer and a water soluble
pore-forming agent. By suspending, instead of dissolving the pore-forming agent,
the resulting coating will contain particles of the pore-formers with a predetermined
size that creates, when disintegrated or dissolved in the body fluid, canals or
a network of pores through the polymer film. Due to this network, the film will
get a good mechanical stability and are left intact after the release of the drug.