The invention is a topical, anti-inflammatory medical, cosmetic, or dermatological preparation comprising at least one compound of the formula (DKH) 1 wherein n is 1 or 2; and R.sub.1 and R.sub.2, independently of each other, are selected from the group consisting of phenyl, 2-toly, 3-tolyl, 4-tolyl, 2-methoxyphenyl, 3-methoxyphenyl, and 4-methoxyphenyl. The invention also includes methods for treating or preventing itchiness, hyperreactive skin conditions, sensitive skin, photostress, impure skin, the effects of UV radiation, and irritation comprising applying said preparation to the skin.