Techniques are provided for determining a capacity allocation in a multi-tiered computing system. In one aspect of the invention, a technique for designing capacity allocation for a multi-tiered computing system, each tier of the computing system having one or more computing devices (e.g., servers), comprises the following steps/operations. Input parameters relating to capacity allocation are obtained. A capacity allocation is computed based on at least a portion of the input parameters, the capacity allocation being computable such that one or more end-to-end performance measures are substantially satisfied for multiple service classes. The capacity allocation computation may minimize a cost function. The capacity allocation computation may also satisfy one or more mean delay guarantees for the multiple service classes, one or more tail distribution guarantees for the multiple service classes, or both one or more mean delay guarantees and one or more tail distribution guarantees for the multiple service classes.