The invention provides cationic cardiolipin compounds, and methods for
synthesizing and using them in liposomal formulation, gene transfection,
etc. In particular, the invention provides liposomes comprising cationic
cardiolipin analog, pharmaceutical compositions comprising cationic
cardiolipin analogs, and methods of using such liposomes and
compositions, in delivering active pharmaceutical agents to treat human
and animal diseases and/or in diagnostic assays.