An advanced patient management system including at least one device that is implanted in a patient, the device being configured to measure physiological attributes of the patient and provide therapy to the patient. The advanced patient management system may also include an interrogator/transceiver unit in communication with the device and a network, the unit being positioned relative to the device to facility communication between the repeater and the device. The advanced patient management system also includes a host, in communication with the device through the network, to store data from the device and to provide a predictive diagnosis of an oncoming event. The interrogator/transceiver unit may include programmable or updateable with software from a computer system or remote host.