A method is provided which in one embodiment can interact with cognitively impaired individuals for various purposes, such as entertainment, education, exercise, and therapeutic treatment. In particular, a method is provided for entertaining or educating cognitively impaired individuals, such as those suffering from Alzheimer's disease. In one embodiment, a sensory presentation can be provided to a cognitively impaired individual to assist the individual in generating a cognitive, emotional, or physical response to the sensory presentation. In an exemplary embodiment, the sensory presentation can be produced based on one or more of the cognitive, cognitive-perceptual, and/or functional abilities retained by the cognitively impaired individuals. Additionally or alternatively, a device and a system is provided to interact with cognitively impaired individuals.