Compounds of the formula below are poly(ADP-ribosyl)transferase (PARP) inhibitors, and are useful as therapeutics in treatment of cancers and the amelioration of the effects of stroke, head trauma, and neurodegenerative disease. ##STR1##

As cancer therapeutics, the compounds of the invention may be used, e.g., in combination with cytotoxic agents and/or radiation.

 
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< Solvent-free room temperature curing reactive systems and the use thereof in the production of adhesives, sealing agents, casting compounds, molded articles or coatings

< Reactive systems that harden at room temperature

> Films produced from substantially linear homogeneous olefin polymer compositions

> Synthetic paper skins, paper and labels containing the same and methods of making the same
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