The invention relates to the heavy duty radial tire with a bead-wind structure. And carcass cords of the carcass extend while inclining to one side in the tire and the other-side inclined region that extends while inclining to the other side with a lowermost position of the bead core in the tire axial direction being substantially the center. Or, the reinforcing ply is similarly inclined as the carcass cords. With this arrangement, it is possible to improve engaging force of the carcass ply or the reinforcing ply to the bead cores so that shifts of the carcass ply in a blow-by direction can be effectively restricted. It is also an object to provide a heavy duty radial tire that is capable of restricting damages of the beads at the inner end positions A.