The invention provides a novel gene, gridlock, and its encoded protein. gridlock plays a role in vascular development and modeling, and a mutation in gridlock has been associated with an aortic arch disease, coarctation. Thus, gridlock nucleic acid molecules and polypeptides can be used in methods of diagnosing, treating, and preventing gridlock-related diseases and conditions, such as aortic arch diseases.

 
Web www.patentalert.com

< Isolated human transporter proteins, nucleic acid molecules, encoding human transporter proteins, and uses thereof

< Mutant carbamoylphosphate synthetase and method for producing compounds derived from carbamoylphosphate

> Methods and compositions for nucleic acid delivery

> Recombinant gelatins

~ 00234