A method and system for optimizing health expenditure by an organization including developing a Cohort-based personnel model for the organization; determining lifecycle health costs based on the personnel model; evaluating impact of a lifestyle program, a best health practices program, and an employee benefits program on the life cycle health costs for a first scenario; and measuring project evaluation criteria for the lifestyle, best health practices, and employee benefits programs. A method and system for integrating health and wealth of an individual including developing a profile regarding health and wealth, and quality of life specifications for the individual; determining a quality of life index based on wealth, best health practices and lifestyle of the individual, wherein the quality of life index includes both health and wealth information; and measuring impacts of the profile, wealth, best health practices and lifestyle of the individual on the quality of life index.