A latch structure for a mobile electronic device (1), for example, a personal digital assistant (PDA) is disclosed. The latch structure comprises a side flange (20) of a cover (10) and a side panel (30). The side flange (20) includes a cantilever (200) and at least a first engaging portion (205). The cantilever has a slanted face (201) and a lock (203) on a free end thereof. The lock has a first ramp (207). The side panel detachably connects to the side flange and defines a hole (301). The side panel includes a second engaging portion (303) and a third engaging portion (305). The hole corresponds to the slanted face. The second engaging portion has a second ramp (307) corresponding to the first ramp of the lock. The lock engages with the second engaging portion in a first position and disengages from the second engaging portion in a second position. The first engaging portion engages with the third engaging portion in the first position and disengages from the third engaging portion in the second position.