Selected heterocyclic compounds are effective for prophylaxis and treatment
of diseases, such as angiogenesis mediated diseases. The invention encompasses
novel compounds, analogs, prodrugs and pharmaceutically acceptable derivatives
thereof, pharmaceutical compositions and methods for prophylaxis and treatment
of diseases and other maladies or conditions involving, cancer and the like. The
subject invention also relates to processes for making such compounds as well as
to intermediates useful in such processes.