The present invention provides an integrated method, implemented over a wide area network or wireless network, comprising a server side and a client side, for user-directed acquisition of reference information, such as dictionary definitions ("look-ups") or language translation, relating to user-selected messages or user-selected text of World Wide Web (Web") site pages. The method steps, for Web use, are integrated into either a server-side web site or into a client-side system. In particular embodiments, reference information relating to user-selected Web page includes high quality multi-lingual translations, explanations, illustration and/or consolidated automatic multi-dictionary definitions, wherein such information is displayed to the user in text, voice, image or multi-media formats. The present invention also provides an apparatus for user-directed acquisition of information relating to user-selected Web page text. The present invention further provides an integrated method, over a wireless network for user-direct acquisition of real-time translation and reference services in both text and voice.