A spark control system and method for an engine having an intake cam phaser and/or an exhaust cam phaser, and having engine sensors, comprises a principal calculation module that determines a principal spark advance value based upon actual rotational position of the cam phasers, and an output calculation module that determines an output spark advance value based upon the principal spark advance value and spark modifiers determined from the engine sensors. The actual rotational positions of the cam phasers are obtained from predictive calculations or rotational position sensors on the cam phasers. The principal calculation module includes two separately calibrated look-up tables, indexed by the actual rotational position of the cam phasers, whose outputs are scaled and combined to determine the principal spark advance. The spark modifiers include temperature base, coolant, induction air temperature, equivalence ratio, and piston slap.