The present invention relates to the use of zeolite ITQ-21 in a process of catalytic cracking of organic compounds. In said cracking process the zeolite ITQ-21 can be present in the catalyst as the sole zeolite component of same of combined with at least one second zeolite component. Moreover, said zeolite ITQ-21 can be present in the catalyst as unmodified zeolite ITQ-21 or as ITQ-21 modified zeolite. The preferred combinations, wherein the zeolite forms part of the cracking catalyst, are those wherein it is combined with at least one second zeolite component. The preferred modifications comprise, for example, a modification by means of post-synthesis treatment with phosphorous or a modification involving the introduction of acid centres. The catalytic process is preferably an FCC or DPC type hydrocarbon cracking process.