The present invention relates to novel compounds, compositions comprising said compounds, and uses thereof, said compounds having the formula: ##STR1##

wherein each X is independently selected from:

  • i) —C(W)2—;
  • ii) —C(O)—;
  • iii) —NR2—;
  • iv) —S—;
  • v) —S(O)—;
  • vi) —S(O)2—;
  • vii) two units, one from each adjacent X unit, can be taken together to form a substituted or unsubstituted double bond having the formula —CWCW—; wherein each W is hydrogen of a unit having the formula —(L2)j—R2, the index j is 0 or 1;
  • R is a carbocyclic or heterocyclic aryl ring;
  • R1 is a cysteine trap;
  • each R2 is independently a suitable substituent; and
  • L, L1, and L2 are linking units.
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