Selected heterocyclic compounds are effective for prophylaxis and
treatment of diseases, such as angiogenesis mediated diseases. The
invention encompasses novel compounds, analogs, prodrugs and
pharmaceutically acceptable derivatives thereof, pharmaceutical
compositions and methods for prophylaxis and treatment of diseases and
other maladies or conditions involving, cancer and the like. The subject
invention also relates to processes for making such compounds as well as
to intermediates useful in such processes.