The present invention relates to the delivery of anti-migraine compounds through
an inhalation route. Specifically, it relates to aerosols containing sumatriptan,
frovatriptan, or naratriptan that are used in inhalation therapy. In a method aspect
of the present invention, sumatriptan, frovatriptan, or naratriptan is administered
to a patient through an inhalation route. The method comprises: a) heating a thin
layer of sumatriptan, frovatriptan, or naratriptan on a solid support to form a
vapor; and, b) passing air through the heated vapor to produce aerosol particles
having less than 5% drug degradation products. In a kit aspect of the present invention,
a kit for delivering sumatriptan, frovatriptan, or naratriptan through an inhalation
route is provided which comprises: a) a thin coating of a sumatriptan, frovatriptan,
or naratriptan composition; and, b) a device for dispending said thin coating as
a condensation aerosol.