Methods for amplifying target nucleic acid sequences using a nucleic acid
polymerase lacking 5 exonuclease activity and a set of oligonucleotide
primers. Preferably, a primer array is used. The primer array contains two sets
of primers. One set contains at least two complementary primers. The other set
contains at least two sense primers. Using the described methods amplification
can be carried out under essentially constant environmental conditions without
the requirement for exonuclease activity or restriction endonu- clease activity.