Disclosed is a method and apparatus for detecting endplates of vertebra, comprising the steps of providing a filtered curvature map derived from filtering an intensity curvature map of a spine image in a direction relative to a spine axis, computing minimum and maximum curvature projections for each point along said spine axis, at a plurality of points on said spine axis, computing a score from said curvature projections, said score indicating the likelihood that the point is located on an endplate, and subjecting said score calculation to at least one of the following constraints (1) that the angle between neighboring endplates not exceed a certain value, and (2) that the variation in height of vertebra of said spine image should satisfy a global model.