Compounds of general formula I[Chemical formula should be inserted here.
Please see paper copy] R1 is selected from any one of phenyl, pyridinyl,
thienyl, furanyl, imidazolyl, pyrrolyl, triazolyl, thiazolyl and pyridine N-oxide;
where each R1 phenyl ring and R1 heteroaromatic ring may
optionally and independently be further substituted by 1, 2 or 3 substituents selected
from straight and branched C1-C6alkyl, NO2, CF3,
C1-C6alkoxy, chloro, fluoro, bromo, and iodo. The substitutions
on the phenyl ring and on the heteroaromatic ring may take place in any position
on said ring systems; are disclosed and claimed in the present application, as
well as salts and pharmaceutical compositions comprising the novel compounds and
their use in therapy, in particular in the management of pain, anxiety and functional
gastrointestinal disorders.
